Projekt

Biodiversity is a sign of ecological health. Models to explain this phenomenon have largely ignored temporal structures, such as the 24 h day. The researchers involved in this project have found that daily, cycling "Zeitgebers" of the circadian clock support microbial co-existence. They will explore this phenomenon through integration of minimalistic systems in vitro, in in vivo genetic models and by using mathematical models. Basic rules of temporal structuring that foster biodiversity, as well as the molecular pathways that are invoked in the process will be identified. This work explores integration of the physical environment into cell biology in a completely novel approach to understanding the foundations of population structure.

• Prof. Dr. Martha Merrow

  Universität München
  Medizin
  Institut für Medizinische Psychologie
  München
  

• Prof. Dr. Matthias Mann

  Max-Planck-Institut für Biochemie
  Dept. Proteomics and Signaltransduction
  Martinsried
  

• Dr. Maria Robles

  Max-Planck-Institut für Biochemie
  Department of Proteomics and Signal Transduction
  München
  

• Prof. Dr. Erwin Frey

  Universität München
  Fakultät für Physik
  Arnold-Sommerfeld-Center
  für Theoretische Physik
  München
  

• Prof. Dr. Garret FitzGerald

  University of Pennsylvania
  Medicine/Systems Pharmacology & Trans Ther
  Institute for Translational Medicine &
  Therapeutics
  SCTR, Bldg 421, Ro0m 10-122
  Philadelphia
  USA
  

• Prof. Amita Sehgal, Ph.D.

  University of Pennsylvania
  Department of Neuroscience
  Perelman School of Medicine
  Smilow Center 10-136
  Philadelphia
  USA