Projekt

Daten zum Projekt

The Fourth Dimension: Integration of time to shape co-operativity and survival in the biosphere

Initiative: "Leben?" - Ein neuer Blick der Naturwissenschaften auf die grundlegenden Prinzipien des Lebens
Bewilligung: 27.03.2017
Laufzeit: 4 Jahre

Projektinformationen

Biodiversity is a sign of ecological health. Models to explain this phenomenon have largely ignored temporal structures, such as the 24 h day. The researchers involved in this project have found that daily, cycling "Zeitgebers" of the circadian clock support microbial co-existence. They will explore this phenomenon through integration of minimalistic systems in vitro, in in vivo genetic models and by using mathematical models. Basic rules of temporal structuring that foster biodiversity, as well as the molecular pathways that are invoked in the process will be identified. This work explores integration of the physical environment into cell biology in a completely novel approach to understanding the foundations of population structure.

Projektbeteiligte

  • Prof. Dr. Martha Merrow

    Universität München
    Medizin
    Institut für Medizinische Psychologie
    München

  • Prof. Dr. Matthias Mann

    Max-Planck-Institut für Biochemie
    Dept. Proteomics and Signaltransduction
    Martinsried

  • Dr. Maria Robles

    Max-Planck-Institut für Biochemie
    Department of Proteomics and Signal Transduction
    München

  • Prof. Dr. Erwin Frey

    Universität München
    Fakultät für Physik
    Arnold-Sommerfeld-Center
    für Theoretische Physik
    München

  • Prof. Dr. Garret FitzGerald

    University of Pennsylvania
    Medicine/Systems Pharmacology & Trans Ther
    Institute for Translational Medicine &
    Therapeutics
    SCTR, Bldg 421, Ro0m 10-122
    Philadelphia
    USA

  • Prof. Amita Sehgal, Ph.D.

    University of Pennsylvania
    Department of Neuroscience
    Perelman School of Medicine
    Smilow Center 10-136
    Philadelphia
    USA