Projekt

Nanodiamonds are biocompatible nanoparticles, which can be functionalized by manifold surface modifications. Therefore, they are an excellent candidate for biomedical and even therapeutic applications. The project aims at developing nanodiamonds labeled by different lattice modifications, such that they are detectable by various techniques, from microscopy and radiography to magnet resonance imaging. Modifying the nanodiamond lattice instead of its surface ensures that the nanoparticle and its label do not dissolve in physiologic environment. Additionally, it does not alter its interactions with the environment and hence the bio-compatibility of the nanoparticle is preserved. A nanoparticle that is not detectable due to surface but to lattice modifications for the first time allows comparable investigations from the subcellular to organism level, eventually leading to the development of nanodiamond based tools for biomedical and therapeutic applications.

• Dr. Patrick Happel

  Universität Bochum
  RUBION
  Gebäude NI 06/265
  Bochum
  

• Dr. Helmut Bühler

  Universität Bochum
  Medizinische Fakultät
  Universitätsklinik Marienhospital
  Klinik für Strahlentherapie und Radio-Onkologie
  Herne
  

• Prof. Dr. Irenaeus Adamietz

  Universität Bochum
  Medizin/Strahlentherapie
  Universitätsklinikum Marienhospital Herne
  Klinik für Strahlentherapie
  Herne
  

• Prof. Dr. Rolf Heumann

  Universität Bochum
  Fakultät für Chemie und Biochemie
  Molekulare Neurobiochemie
  NC7/174 Biochemie II
  Bochum
  

• Prof. Dr. Fedor Jelezko

  Universität Ulm
  Institut für Quantenoptik
  Ulm
  

• Dr. Boris Naydenov

  Universität Ulm
  Fakultät für Naturwissenschaften
  Institut für Quantenoptik
  Ulm
  

• Prof. Dr. Jan Meijer

  Universität Leipzig
  Fakultät für Physik und Geowissenschaften
  Felix-Bloch-Institut für Festkörperphysik
  Abt. Nukleare Festkörperphysik
  Leipzig
  

• Prof. Dr. Anke Krueger

  Universität Würzburg
  Fakultät für Chemie und Pharmazie
  Institut für Organische Chemie
  Würzburg
  

• Optically induced dynamic nuclear spin polarisation in diamond.