Projekt

Daten zum Projekt

Coaxial 3D printing of actuating electroactive scaffolds for muscle regeneration

Initiative: Integration molekularer Komponenten in funktionale makroskopische Systeme (beendet, nur noch Fortsetzungsanträge)
Bewilligung: 26.06.2017
Laufzeit: 3 Jahre

Projektinformationen

Electroactive polymers have been investigated as stimuli-responsive materials for many years but their functional application has fallen short of expectations. The project aims at a new approach combining synthesis of conductive polymers, state of the art materials science and advanced 3D printing to utilize nanoscale effects in microscale processing, that can be electrically simulated to actuate on the macroscale. Using the newly developed 3D printing technique of melt electrospinning writing, coaxial (core-shell) fibres that comprise of a stimuli responsive shell surrounding a conductive polymer core will be prepared. Flow induced crystallization - already observed with melt electrospinning writing - aligns nanoscopic structures so that they can macroscopically electromodulate. These 3D-printed biomedical materials will be coated with a biocompatible hydrogel to integrate within living tissue/cells. The outcome of a successful project is a strong foundation for manufacturing new electroactive polymers that can then be tailored for use in many different life science applications.

Projektbeteiligte

  • Prof. Dr. Paul Dalton

    Universitätsklinikum Würzburg
    Lehrstuhl für Funktionswerkstoffe der Medizin
    und der Zahnheilkunde
    Würzburg

  • Prof. Dr. Robert Luxenhofer

    Universität Würzburg
    Fakultät für Chemie und Pharmazie
    Lehrstuhl für Chemische Technologie
    der Materialsynthese
    Alte Chemie
    Würzburg

  • Professor Rylie Green, Ph.D.

    Imperial College London
    Faculty of Engineering
    Department of Bioengineering
    B206 Bessemer Building
    South Kensington Campus
    London
    Grossbritannien

Open Access-Publikationen