Projekt

Daten zum Projekt

Illuminating the brain - Unmasking the Enigmatic Role of CRY as a Light-Sensitive Magnetoreceptor

Initiative: Pioniervorhaben Exploration
Ausschreibung: Natur- und Lebenswissenschaften
Bewilligung: 04.07.2024
Laufzeit: 3 Jahre

Projektinformationen

The use of modern technologies such as mobile phones results in the exposure of the human brain to artificial blue light and electromagnetic radiation (EMR), which are distinct from the natural stimuli that our brains have evolved to respond to over the course of evolution. Although the effects may not be immediately apparent, it is probable that our brains are being affected in ways that are not yet fully understood. The project team is utilizing animal model experiments to investigate the effects of overexposure to blue light and EMR on the brain. The project team is focusing on oligodendrocytes and the development of myelin, which protects nerve cells. If these oligodendrocytes are damaged or stressed, this can have a negative impact on the neurons. The current studies indicate that in these cells, the protein cryptochrome, which is capable of sensing light and magnetic fields, malfunctions when there is an excess of blue light and EMR. The project's objective is to bridge the knowledge gap regarding the molecular effects of artificial blue light and EMR exposure on myelin development, thereby providing insights into brain health in the present era.

Projektbeteiligte

  • Dr. Sinead O'Sullivan

    Deutsches Zentrum für Neurodegenerative
    Erkrankungen e. V. (DZNE)
    Standort Bonn
    Bonn