Projekt

Helicobacter pylori is a bacterium that colonizes the gastric mucosa of over one half of the global human population. It has been shown that human populations are infected by these bacteria that are specific for each continent and that the genetic diversity of H.pylori is a useful tool for distinguishing human populations and identifying traces of ancient and recent human migrations. Human Genetic analyses indicate that the human gene pool in Central Asian and Caucasian populations is highly diverse and is intermediate between Europe and Asia, with components from both sources. An analysis of the diversity of H.pylori from Central Asians and Caucasians could test different hypotheses regarding the evolution of theses populations and hopefully reveal addition details on the history of human migrations to and from these regions.

• Prof. Dr. Sebastian Suerbaum

  Medizinische Hochschule Hannover
  Institut für Medizinische Mikrobiologie
  und Klinische Epidemilogie
  Hannover
  

• Dr. Tamara Aripova

  Uzbek Academy of Sciences
  Institute of Immunology
  Taschkent
  Usbekistan
  

• Dr. Tatyana Hegay

  Uzbek Academy of Sciences
  Institute of Immunology
  Taschkent
  Usbekistan
  

• Dr. Daniel Falush

  University of Oxford
  Department of Statistics
  Peter Medawar Building
  for Pathogen Research
  Oxford
  Grossbritannien