Projekt

The central aim of the professorship is the development of nanoporous nanocapsules with controlled pore size and pore density using a toolbox based on organic and inorganic nanoparticle building blocks.The size control of the pores on the nanometer scale is still a challenging problem. As sacrificial templates for the design of novel nanocapsules the spherical protein cage of the cow pea mosaic virus (CPMV) and gold nanoparticles are used. Another goal is the self-assembly of polymer-modified CPMV and other bionanoparticles at emulsion droplet interfaces to build novel microcapsules and furthermore allow in-situ encapsulation of target molecules in solution. The biological and chemical addressability will be maintained throughout the capsule built-up. The mechanical properties as well as the porosity of the capsules will be controlled via polymer-modification of the bionanoparticle building block. Transferring the assembly process onto a solid substrate allows the fabrication of a nanoporous membrane, where the bionanoparticle building blocks serve as sacrificial template for the pores. Those can be further functionalized. Along these lines, novel responsive capsules for "targeted drug delivery"-applications will be realized.

• Prof. Dr. Alexander Böker

  Universität Bayreuth
  Lehrstuhl für Physikalische Chemie II
  AG Böker
  Bayreuth