Projekt

Heterogeneous membranes play a crucial role for many cellular processes and in biorelated nanotechnology. This project builds upon existing methodology and aims at the development of a genuine multiscale method, which is capable of including prior knowledge and allows to study the structure and dynamics of complex membrane systems on different scales. A "horizontal coupling" strategy is envisaged, that merges different levels of representation (originating from molecular field, phenomenological and coarse-grained particle descriptions) and different kinetic descriptions (diffusive Langevin and hydrodynamic Lattice-Boltzmann field) in a consistent way. This project encompasses a modular approach and validation of all elementary steps, i.e. for membranes of increasing complexity, using experiments (in Bayreuth and Leiden) and literature data. The new approach will ultimately be applied for a system of high scientific impact: to unravel the mechanisms in SNARE-mediated membrane fusion.

• Prof. Dr. Friederike Schmid

  Universität Mainz
  Fachbereich 08
  Institut für Physik
  Mainz
  

• Prof. Dr. Alexander Böker

  DWI - Leibniz-Institut für
  Interaktive Materialien e.V.
  Institut für Physikalische Chemie (IPC)
  Lehrstuhl für Makromolekulare Materialien
  und Oberflächen
  Aachen
  

• Prof. Dr. Andrei V. Zvelindovsky

  University of Central Lancashire
  School of Computing, Engineering &
  Physical Sciences
  Preston
  Grossbritannien
  

• Agur Sevink, Ph. D.

  Leiden University
  Faculty of Mathematics and Natural Sciences
  Leiden Institute of Chemistry/Soft Matter
  Chemistry
  Leiden
  Niederlande