Daten zum Projekt
| Initiative: | Kurswechsel – Forschungsneuland zwischen den Lebenswissenschaften und Natur- oder Technikwissenschaften |
|---|---|
| Ausschreibung: | Qualifizierungskonzepte |
| Bewilligung: | 05.07.2019 |
| Laufzeit: | 3 Jahre |
Projektinformationen
The qualification concept revolves around an ambitious research question at the interface of microtechnology and biomechanics. Together with biology experts from Stanford University and the University of Washington, the group will attempt to decode the mechanisms of Lyme disease via advanced sensing platforms. Using endothelium-on-chip microfluidic systems, the team will study the mechanisms of endothelial infection and dissemination of Borrelia Burgdorferi, the causative agent of Lyme. This will be the first attempt to decipher the intricate interplay between endothelial biomechanics, extracellular matrix stiffness, and their impact on disease pathogenesis and spread. These studies can facilitate the design of diagnostic tools and pharmaceutical products. Additionally, this qualification concept includes acquisition of interdisciplinary skills through research stays, workshops, and conferences as well as mentoring.
Projektbeteiligte
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Prof. Dr. Iordania Constantinou
Technische Universität Braunschweig
Faculty of Mechanical Engineering
Institut für Mikrotechnik
Braunschweig
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Dr. Effie Bastounis, Ph.D.
University of Washington
Department of Biology
Seattle
USA
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Dr. Michal Tal, Ph.D.
Stanford University School of Medicine
Stem Cell and Regenerative Medicine
Stanford
USA